Best Wrinkle Cream

simply the best active ingredient in anti-aging skin care treatments

Use The most beneficial ingredient in Topical anti-wrinkle Skin care Products for Prevention and Treatment of Aging Skin 

Clinical studies, hands down, have proven that the best wrinkle cream is formulated with retinoids (a form of vitamin A) to reduce fine lines and wrinkles, help diminish age spots and makes your skin plumper and smoother by stimulating skin cells to make more collagen. 

Symptoms of Aging Skin

Specialists recommend that patients concerned with symptoms of aging skin start a rejuvenation regime by using daily sunscreen.

Prevention is KEY! 

Prior to daily sunscreen, a morning a topical moisturizer infused with antioxidants (like Vitamin C) and a cocktail of other active anti-aging ingredients is highly recommended.

Every night, use the best wrinkle cream treatment that is formulated with a topical retinoid (vitamin A).  It's essential for an effective anti-aging skin care routine. 

Supplementing a rejuvenation routine with other effective active ingredients, depending on your skin type and aging skin concerns, includes options such as:

  • Alpha Hydroxy Acids
  • Alpha-Lipoic acid 
  • Tea Extracts
  • Grape Seed Extract
  • Coenzyme Q-10 (CoQ-10) 
  • Peptides
  • Salicylic Acid 
  • Hyaluronic Acid
  • Niacinamide

The Mayo Clinic provides a comprehensive guide to younger skin:

The US National Library of Medicine, registered clinical trial, concluded that of the most commonly used active anti-aging ingredients, the most improvement of naturally aged skin is vitamin A (retinol).


The NIH study concluded:
"Topical retinol improves fine wrinkles associated with natural aging. Significant induction of glycosaminoglycan, which is known to retain substantial water, and increased collagen production are most likely responsible for wrinkle effacement. With greater skin matrix synthesis, retinol-treated aged skin is more likely to withstand skin injury and ulcer formation along with improved appearance."

The retinoid family comprises vitamin A (retinol) and its natural derivatives such as  retinoic acid.  Retinol is used in over-the-counter anti wrinkle skincare treatments in concentrations of .25% up to 1%.

Tretinoin is a prescription strength retinoid used to treat a variety of skin conditions such as acne, psoriasis, and photoaging. 

OTC Treatments by Concentration of Retinol


  .25% Retinol        

Search for Retinol- Vitamin A - treatments: 

Quick Search for the best wrinkle cream formulated with Retinol:

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